Skip to Main content Skip to Navigation
Journal articles

Synthesis of multilamellar walls vesicles polyelectrolyte-surfactant complexes from pH-stimulated phase transition using microbial biosurfactants

Abstract : Multilamellar wall vesicles (MLWV) are an interesting class of polyelectrolyte-surfactant complexes (PESCs) for wide applications ranging from house-care to biomedical products. If MLWV are generally obtained by a polyelectrolyte-driven vesicle agglutination under pseudo-equilibrium conditions, the resulting phase is often a mixture of more than one structure. In this work, we show that MLWV can be massively and reproductively prepared from a recently developed method involving a pH-stimulated phase transition from a complex coacervate phase (Co). We employ a biobased pH-sensitive microbial glucolipid biosurfactant in the presence of a natural, or synthetic, polyamine (chitosan, poly-L-Lysine, polyethylene imine, polyallylamine). In situ small angle X-ray scattering (SAXS) and cryogenic transmission electron microscopy (cryo-TEM) show a systematic isostructural and isodimensional transition from the Co to the MLWV phase, while optical microscopy under polarized light experiments and cryo-TEM reveal a massive, virtually quantitative, presence of MLWV. Finally, the multilamellar wall structure is not perturbed by filtration and sonication, two typical methods employed to control size distribution in vesicles. In summary, this work highlights a new, robust, non-equilibrium phase-change method to develop biobased multilamellar wall vesicles, promising soft colloids with applications in the field of personal care, cosmetics and pharmaceutics among many others.
Complete list of metadatas

Cited literature [87 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-02905980
Contributor : Niki Baccile <>
Submitted on : Thursday, July 23, 2020 - 8:27:28 PM
Last modification on : Tuesday, November 10, 2020 - 5:05:28 PM

File

Manuscript_+_Supp_Info.pdf
Files produced by the author(s)

Identifiers

Citation

Chloé Seyrig, Patrick Le Griel, Nathan Cowieson, Javier Perez, Niki Baccile. Synthesis of multilamellar walls vesicles polyelectrolyte-surfactant complexes from pH-stimulated phase transition using microbial biosurfactants. Journal of Colloid and Interface Science, Elsevier, 2020, 580, pp.493-502. ⟨10.1016/j.jcis.2020.07.021⟩. ⟨hal-02905980⟩

Share

Metrics

Record views

72

Files downloads

70