Carbon Nanotubes-Hydroxyapatite Nanocomposites for an Improved Osteoblast Cell Response - Archive ouverte HAL Access content directly
Journal Articles Journal of Nanomaterials Year : 2016

Carbon Nanotubes-Hydroxyapatite Nanocomposites for an Improved Osteoblast Cell Response

(1) , (1) , (2) , (3, 4) , (3, 4) , (5) , (2) , (2)
1
2
3
4
5

Abstract

An alternative and simple coprecipitation method was developed to obtain carbon nanotube-hydroxyapatite (CNTs:HAp) based nanocomposites. The incorporation of CNTs (in a concentration of 5% and 10% of total weight of the nanocomposite) and their impact on both structural and biological properties were studied by using a set of standard complementary biological, microscopic, and spectroscopic techniques. The characteristic peaks of carbon structure in CNTs were not observed in the CNTs-HAp composites by X-ray diffraction analysis. Moreover, FTIR and Raman spectroscopies confirmed the presence of HAp as the main phase of the synthesized CNTs:HAp nanocomposites. The addition of CNTs considerably affected the nanocomposite morphology by increasing the average crystallite size from 18.7 nm (for raw HAp) to 28.6 nm (for CNTs:HAp-10), confirming their proper incorporation. The biocompatibility evaluation of CNTs:HAp-5 and CNTs:HAp-10 nanocomposites included the assessment of several parameters, such as cell viability, antioxidant response, and lipid peroxidation, on human G-292 osteoblast cell line. Our findings revealed good biocompatibility properties for CNTs:HAp nanocomposites prepared by the coprecipitation method supporting their potential uses in orthopedics and prosthetics.
Fichier principal
Vignette du fichier
3941501.pdf (5.03 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Loading...

Dates and versions

insu-01294590 , version 1 (29-03-2016)

Identifiers

Cite

Sabrina Constanda, Miruna Silvia Stan, Carmen Steluta Ciobanu, Mikael Motelica-Heino, Régis Guégan, et al.. Carbon Nanotubes-Hydroxyapatite Nanocomposites for an Improved Osteoblast Cell Response. Journal of Nanomaterials, 2016, Article ID 3941501, 10 p. ⟨10.1155/2016/3941501⟩. ⟨insu-01294590⟩
156 View
429 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More