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Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions

Abstract : Highlights d Joint X-ray/neutron structure of bacterial lectin in apo and complex form d Perdeuterated lectin and sugar improve the quality of neutron density maps d Fucose methine and methyl groups are involved in CH-p interactions with tryptophan d Room temperature data avoid glycerol-induced alternate loop conformations
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https://hal.archives-ouvertes.fr/hal-03180319
Contributor : Anne Imberty <>
Submitted on : Wednesday, March 24, 2021 - 9:50:42 PM
Last modification on : Wednesday, September 22, 2021 - 9:14:05 AM

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Lukas Gajdos, Matthew Blakeley, Atul Kumar, Michaela Wimmerová, Michael Haertlein, et al.. Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions. Structure, Elsevier (Cell Press), 2021, ⟨10.1016/j.str.2021.03.003⟩. ⟨hal-03180319⟩

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